Vitamin B is a soluble vitamin taking part in the cellular machinery. It is composed of eight different groups of vitamins involved in different anabolic and catabolic processes. One of the vital entailing effects of vitamin B is predominantly found in the brain cells.
As we all know the brain is a vital organ which occupies 2% of the overall body weight accounting to have 20% of the energy expenditure.
The ubiquitous function of Vitamin B has a profound effect on the cognitive function of the brain. In this article, we are going to investigate the plethora of function exhibited by vitamin B.
Role Of Vitamin B1 Or Thiamine In Brain Health
It is vital coenzyme taking part in the pentose phosphate pathway that is crucial to synthesize steroids, fatty acids, aromatic compounds of amino acids and nucleic acids. Vitamin B is majorly acting as a core enzyme to carry out the enzymatic processes. These are bioactive precursors for a wide number of neurotransmitters that supply the brain. Thiamine is thus found to support the structural built up of the membranes of neuroglia and neurons comprising the brain.
Vitamin B1 sources include nuts, oats, oranges, egg, legumes, yeast peas and so on.
Use Of Vitamin B3 Or Niacin In Cognitive Function
Cellular functioning of the brain is inclined to niacin as it is a major component to produce NAD and NADPH responsible to derive energy to the body metabolism. Besides, they also shield our body from the superoxide radicals. The reduction in the intake of niacin proves to be a major deprivation of the receptors like the NIACRI receptor that causes schizophrenia and Parkinson’s disease. Some of the recognized food sources for vitamin B3 are peanuts, brown rice, fish, mushrooms, avocados, chicken and so on.
Role Of Vitamin B5 Or The Pantothenic Acid In Brain Development
It is responsible to synthesize the coenzyme A that is important in various mechanisms involving the oxidative metabolism. It restricts the structure of the brain to get depleted as it is involved in the synthesis of phospholipids, amino acids, fatty acids, and cholesterol. Thus they are responsible for a variety of steroid hormone and neurotransmitters.
The Function Of Vitamin V6 or Pyridoxine In Cognitive Response
Vitamin B6 is mainly present in seafood, poultry meats, legumes, soy, and nuts and is a crucial cofactor responsible to regulate folate cycle. It is a rate-limiting factor for the regulation of the neurotransmitter like the serotonin, dopamine, GABA and so on. Such downregulation may lead to neural transmission inhibition causing you to spend restless nights. It is a major player in the uptake of glucose by the brain that may lead to pathological disease like cognitive declining or dementia.
Role Of Vitamin B7 Or Biotin In Brain Development
A healthy brain is supplied with glucose to be kept functioning. Biotin keeps pace with the gluconeogenesis, glucose uptake by the hepatocyte and regulating the pancreatic beta cell to produce insulin. Low circulation of biotin has a correlating effect in causing diabetes type II.
Vitamin B7 sources include fortified cereals, corn, eggs, royal jelly, soy and so on.
Use Of Vitamin B9 Or Folate In Regulating Brain Function
Folate function with correspondence to vitamin B12 that cause trapping of folate as methyltetrahydrofolate. The result of the folate deficiency causes a down-regulation of pyrimidine and purine biosynthesis that is the basic building block of the DNA causing methylation of the tissues in the brain. Thus, the stability of the brain is impaired leading to atrophy of the brain. It also can compromise with the integrity of brain and stability of the action potential of the neurons is lost. This is even more severe as it may cause development disorder in the fetus.
The eminent source of folate can be obtained from lentils, spinach, broccoli, mangoes, oranges, sweet corn and so on.
The Function Of Vitamin B12 Or The Cobalamin In Neural Control
It is interlinked to function with the folate to carry out the methionine cycle.It is a necessary cofactor that is responsible to covert the amino acid into neurotransmitters like dopamine, melatonin, serotonin, and so on. It causes some major neurological decline before the occurrence of hematological alteration. Some of the sources of Vitamin B12 include meat, fish, milk and milk products.
It has been found that cellular uptake of the vitamin B is regulated by the brain to a wide extent. This is because the concentration if the folate, pantothenic acid and biotin derivatives found in brain accounts to be greater than the blood. This makes it evident that vitamin B is necessary for keeping the brain healthy. The homocysteine hypothesis holds the fact that vitamin B has a long lasting impact on the brain function.